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Metabolic Health Bundle

Third-party tested

Founded by Dr Elena Seranova

30-day guarantee

Purchase options
£109.00/ bundle

Free UK delivery

This bundle unites NMN, TMG, and Berberine to promote balanced metabolism, stable energy, and long-term cellular health.

Benefits:

  • Optimises Metabolism: Supports healthy blood sugar and lipid balance.

  • Enhances NAD+ Production: NMN restores cellular energy and vitality.

  • Supports Methylation: TMG contributes methyl groups for DNA repair.

  • Activates Longevity Pathways: Berberine triggers AMPK and autophagy for cellular renewal.

  • Improves Focus & Energy: Restores clarity and motivation throughout the day.

Includes:

  • NMN contains NMN, Capsule Shell (Vegetable Cellulose).

  • TMG contains Trimethylglycine Anhydrous (Betaine), Microcrystalline Cellulose (Bulking agent), Vegetable Capsule Shell (Hydroxypropyl Methylcellulose), Bamboo Silica (Anti-caking agent).

  • Berberine with Milk Thistle contains Berberine HCL, Silymarin/Milk Thistle, Microcrystalline Cellulose (Bulking agent), Capsule Shell (Vegetable Cellulose).

All products are Vegan, Non-GMO, and Allergen-Free.
Free from gluten, soy, nuts, fish, shellfish, and dairy.
Third-party tested and packaged in a GMP-certified UK facility.

Inside your bundle

Meet your daily routine

A closer look at each product in your Metabolic Health Bundle.

NMN supplement capsules 500mg

NMN

Energy starts in your cells. Supports NAD+ production for cellular energy and vitality, underpinning the bundle’s metabolic support.

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Product benefits

  • Enhanced Energy Levels
  • Focus & Concentration
  • Activate Collagen Production
  • Increased Vitality
TMG (Trimethylglycine) | 500 mg | 90 Capsules

TMG (Trimethylglycine)

Keep cellular maintenance moving. Provides methyl groups for DNA repair, supporting methylation alongside NMN.

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Product benefits

  • Focus & ADHD Support
  • DNA Repair
  • Liver Health
  • NMN Metabolism Boost
Berberine 400mg with Milk Thistle

Berberine with Milk Thistle

Balance for your metabolism. Supports healthy blood sugar and lipid metabolism, rounding out the bundle’s focus on metabolic health.

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Product benefits

  • Blood Sugar Regulation
  • Weight Loss
  • Autophagy Activation

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Customer reviews

What customers notice.

Read reviews on Trustpilot

I’m not tired in the evenings anymore

“I started NMN because my energy was becoming noticeably less reliable, especially in the afternoon. After the first month, my boyfriend noticed that I’m not tired in the evenings anymore. The difference is not a stimulant rush; I simply feel more capable of sustaining my day, and not feeling the decrease in energy after 3pm.”

NMN 500 mg

Something I take automatically alongside my morning NMN

“I added TMG because I was already taking NMN and wanted a more complete protocol. After 2 weeks, I noticed about 20% more endurance at the gym. It is now something I take automatically alongside my morning NMN.”

TMG

Easier to remain consistent with my eating routine

“I started taking this because I was struggling with sugar cravings, and didn’t want to go on GLP1s. After about 10 days, I noticed that I wasn’t craving a dessert post lunch. The difference has made it easier to remain consistent with my eating routine.”

Berberine + Milk Thistle

The consistency is what made me reorder

“I had previously tried a cheaper NMN product and felt very little. With NMN Bio, I began noticing more alertness and energy after the first week. The third-party testing and UK manufacturing were what convinced me to try it, but the consistency is what made me reorder. I’ve been on monthly subscription for over a year, and this is my go to supplement for maintaining my energy levels.”

NMN 500 mg

Without adding complexity

“TMG is not the kind of supplement that produces a dramatic immediate sensation. For me, the difference has been in better digestion, so I take it with my meals. I value that it supports the rest of my routine without adding complexity.”

TMG

I take it with my meals

“I had used berberine before, but I liked that this formulation also included milk thistle. I take it with my meals, and the main difference I’ve noticed is that I don’t get upset stomach anymore.”

Berberine + Milk Thistle

The most noticeable difference has been faster recovery

“I’m 42 and train 3 times a week. Since adding NMN 500 mg, the most noticeable difference has been faster recovery, and being able to push at every workout. I still do the fundamentals, but this has become one of the few supplements I take every morning without forgetting.”

NMN 500 mg

Easy to take and combine well with NMN

“I originally purchased TMG after reading about methylation support. What made me continue was an effect on focus and concentration. The capsules are easy to take and combine well with NMN.”

TMG

It has complemented both

“This has not replaced eating well or exercising, but it has complemented both. Over about 3 weeks, I noticed a change in my appetite, like I am more in control. I would recommend tracking results rather than expecting an overnight transformation.”

Berberine + Milk Thistle

What I noticed was more practical

“I didn’t suddenly feel ten years younger. What I noticed was more practical: I wasn’t tired anymore. After stopping for 2 weeks, I noticed that I feel different, and exhausted at the end of the day, which convinced me it had been contributing more than I realised.”

NMN 500 mg

A more considered approach

“I had been taking NMN on its own for about 2 years before adding TMG. After combining them, I noticed better sleep, especially if I switch the TMG to evening. It feels like a more considered approach than simply increasing my NMN dose.”

TMG

Easy to keep in my routine

“I was initially concerned that berberine might be difficult on my stomach. My experience has been great with this product! After adjusting for carb heavy meals, it became easy to keep in my routine.”

Berberine + Milk Thistle

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Metabolic Health Bundle Answers

FAQ

Explore the NMN, TMG and Berberine combination, with practical answers about daily use and timing.

Does NMN have any known side effects?

The first human safety trial of NMN in humans was published in 2019 and showed that a single dose of up to 500mg was tolerable.

NMN has been proven safe in high dosages up to 1.2g a day in human clinical studies. Furthermore, multiple health benefits have been demonstrated in humans as well. A study in prediabetic, postmenopausal, obese or overweight women showed that after 10 weeks of NMN supplementation, the volunteers had increased insulin sensitivity. Same study showed that NMN supplementation was able to stimulate the collagen production pathway, suggesting the compound's role in healthy aging (and appearance of skin).

A study in elderly men over 65 showed that NMN supplementation protects against age-related muscle loss. Another study in healthy, adult volunteers of both sexes confirmed that NMN increases endurance, cardiovascular fitness and aerobic capacity in amateur runners. 

Why should I take NMN before breakfast?

It increases absorption.

How much NMN should I take?

If you're younger than 35, you can start with 250mg/day and after 1-2weeks increase to 500mg to see what feels better.If you're older than 35, start with 500mg/day, then increase to 1g to see what feels better.

Should I take one capsule in the morning and one in the afternoon?

No. Take your NMN in the morning to synchronize your NMN consumption with your Circardian rhythms.

Should I break down the capsule for better absorption?

Dr David Sinclair and our founder Dr Elena Seranova don't bother and just take the capsule. There are actually no studies showing that sublingual powder or powder intake results in better absorption than the capsule.

What can amplify the effect of NMN supplementation?

Along with your NMN, take one tablespoon of extra virgin olive oil in the morning. Oleic acid, one of the ingredients in olive oil, is also shown to activate the SIRTUINS, the so-called longevity genes.

In addition, by supplementing with TMG (Trimethylglycine), you increase the methyl groups available in the cell (which NMN utilises). Adding TMG to your NMN supplementation is an excellent way to boost NMN efficiency and ensure balanced homocysteine levels.

DISCLAIMER

Our formulations are backed by scientific research conducted by Dr. Elena Seranova and other researchers. While these studies support the potential benefits of individual ingredients, the statements made on this website have not been evaluated by regulatory authorities such as the FSA, FDA, MHRA, EMA, or their equivalents in other jurisdictions. These products are not intended to diagnose, treat, cure, or prevent any disease.

All information provided is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely solely on this content when making health-related decisions.

Consult your healthcare provider before beginning any new supplement regimen, especially if you are pregnant, nursing, taking medication, or have a known medical condition. Do not discontinue or alter any prescribed medication without first consulting a qualified medical professional.

Product claims and regulatory status may vary by country. It is the responsibility of the purchaser to ensure that use of these products is compliant with local laws and regulations.