Maintaining a healthy body and healthy weight protects us from many illnesses. Managing blood sugar and ensuring you don’t develop insulin resistance is one of the most crucial things you can do for your longevity and increasing your healthspan (the amount of time you spend in good health over the course of your life).
There are tens of human clinical studies looking into diabetic patients and prediabetics, and how they respond to Berberine supplementation. Overall, findings show that Berberine is significantly improving markers related to blood sugar control like HbA1c, fasting plasma glucose and 2-hour postprandial blood glucose amongst others. Over this meta-analysis of 46 studies, Berberine demonstrated strong evidence of improving glycemic control and overall health in thousands of participants.
In a human study of 37 men and women with metabolic syndrome took 300 milligrams of Berberine, three times a day for three months. The study concluded that they all lost an average of two inches off their waist and their BMIs went from the obese to the overweight category.
In a recent study (2020), 900 people in China between the ages of 18-75 had polyps removed during a colonoscopy. They were randomly given either 300 milligrams of Berberine twice daily or a placebo. The participants were then followed up the first year and again, the second year. The study found that none of the participants developed colorectal cancer, however, the participants taking the Berberine had fewer recurrent polyps at 36%, compared to the placebo participants with 47%.
PubMed shows the number of papers published on Berberine each year. In 2020, an astonishing 630 papers were published! As time progresses, more and more people will be aware of the outstanding benefits of supplementing with Berberine.
References
Noncommunicable Diseases
National Diabetes Statistics Report
Type 2 diabetes and quality of life
The metabolism of berberine and it’s contribution to the pharmacological effects
Herbal Management of hepatocellular carcinoma through cutting the pathways of the common risk factors
Blood sugar regulation as a key focus for cardiovascular health promotion and prevention : an umbrella review
Extracting the benefits of berberine for colorectal cancer
Lipid-lowering effect of berberine in human subjects and rats
The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension