Endurance Bundle - Tackle those workouts with great endurance and recovery.
The Endurance Bundle is designed to cover all the needs your body has when it comes to Endurance so you can remain energetic throughout your workouts, be able to increase the intensity of your workouts without compensating for fatigue and helps you with faster recovery so you can hit the gym more often and enjoy what you love most in your lifestyle without feeling lethargic or out of energy.
As we age from 25 years old, our hormone and NAD+ levels are significantly decreasing. NAD+ (nicotinamide adenine dinucleotide) is a molecule found in every living cell in our bodies. It plays a crucial role in a wide range of cellular processes, including energy metabolism, DNA repair, and cellular signaling. Decline in NAD+ leads to inevitable health and energy decline. The result? More fatigue, longer recovery times (from both gym and night outs), less concentration and energy throughout the day. Sounds familiar? By the time we are 27, everyone has experienced these signs of aging.
You can improve your overall health, boost energy levels, and protect your cells from damage and disease with NMN Bio’s NAD+ supplement. This essential molecule is implicated in over 50% of all your cellular functions, and is crucial for energy production. And for keeping your cells healthy. In other words, you can now slow down your aging process, while maintaining peak performance & competitive edge through your 30s, 40s, 50s and beyond!
Quercetin decreases oxidative stress due to its antioxidant properties, which are needed to reduce recovery time after training. The NMN Bio’s Quercetin is combined with Vitamin C, which is also an antioxidant, providing additional benefits to the supplement and increasing Quercetin’s uptake in the body.
One cause of delayed recovery during training is partly related to oxidative stress, and Quercetin is associated with antioxidant and anti-inflammatory properties. Quercetin acts as a scavenger for reactive oxygen species protecting against lipid peroxidation.
The Endurance bundle includes our 2 best selling and effective products:
- NMN - The King of Anti-Aging. Nourish your cells and boost your NAD+, the most essential component of human metabolism. Double your NAD+ levels in 2 weeks and feel your best while getting things done. The best remedy for getting rid of your need for an afternoon nap.
- QUERCETIN - Get rid of “Zombie” cells that cause increase in inflammation, a major driver of aging. Perhaps the most potent anti-inflammatory natural compound, proven to boost immunity
NMN boosts “oxygen uptake (VO2), percentages of maximum oxygen uptake (VO2max), power at first ventilatory threshold, and power at second ventilatory threshold.”.
Imagine going on your 10km run without having to push through that uncomfortable feeling of breathlessness after 10 minutes. If you could delay that to 30 minutes how would you feel? An increased ventilatory threshold gives you this.
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NMN human clinical trials
NMN has been proven safe in high dosages up to 1.2g a day in human clinical studies. Furthermore, multiple health benefits have been demonstrated in humans as well. A study in prediabetic, postmenopausal, obese or overweight women showed that after 10 weeks of NMN supplementation, the volunteers had increased insulin sensitivity. The same study showed that NMN supplementation was able to stimulate the collagen production pathway, suggesting the compound's role in healthy aging (and appearance of skin).
A study in elderly men over 65 showed that NMN supplementation protects against age-related muscle loss. Another study in healthy, adult volunteers of both sexes confirmed that NMN increases endurance, cardiovascular fitness and aerobic capacity in amateur runners. Moreover, a recent study in both humans and mice, demonstrated lengthening of telomeres in both humans and mice after NMN supplementation. Telomeres are the caps at the end of our chromosomes and are essential for cellular health and healthy aging. The longer they are, the more we live!
References
- Safety study in healthy Japanese men
- Efficacy study in prediabetic, post-menopausal, obese or overweight women, demonstrating increase in insulin sensitivity. Same study showed NMN is stimulating the collagen production pathway.
- Efficacy study in elderly men (over 65), showing protection against age-related muscle loss
- Efficacy study in healthy adults showing improved cardiovascular fitness, increased aerobic capacity and endurance in amateur runners
- Efficacy study in humans and mice showing lengthening of telomeres in a dose dependent manner after 30, 45 and 60 days
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Quercetin Human Clinical Trials
Quercetin has been proven safe in high doses up 1000mg to in human clinical studies, with a high number of studies showing no or few adverse effects and/ or toxicity.
In one study, 84 patients with idiopathic hypertension and gout took 1000mg quercetin twice a day for 6 months and then 500mg twice a day for another 6 months (12 months in total). Results showed improvement of cardiac diastolic function, purine metabolism, renal function and normalization of blood pressure.
Another study saw 50 women with rheumatoid arthritis who took 500mg quercetin a day for 8 weeks display lower plasma levels and lessened pain.
References
Quercetin as an antiinflammatory analgesic
Role of quercetin in cardiovascular diseases
Therapeutic potential of quercetin as a cardiovascular agent
Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application.
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FAQ
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Does NMN have any known side effects?
The first human safety trial of NMN in humans was published in 2019 and showed that a single dose of up to 500mg was tolerable.
NMN has been proven safe in high dosages up to 1.2g a day in human clinical studies. Furthermore, multiple health benefits have been demonstrated in humans as well. A study in prediabetic, postmenopausal, obese or overweight women showed that after 10 weeks of NMN supplementation, the volunteers had increased insulin sensitivity. Same study showed that NMN supplementation was able to stimulate the collagen production pathway, suggesting the compound's role in healthy aging (and appearance of skin).
A study in elderly men over 65 showed that NMN supplementation protects against age-related muscle loss. Another study in healthy, adult volunteers of both sexes confirmed that NMN increases endurance, cardiovascular fitness and aerobic capacity in amateur runners.
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Why should I take NMN before breakfast?
It increases absorption.
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How much NMN should I take?
If you're younger than 35, you can start with 250mg/day and after 1-2weeks increase to 500mg to see what feels better.If you're older than 35, start with 500mg/day, then increase to 1g to see what feels better.
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Should I take one capsule in the morning and one in the afternoon?
No. Take your NMN in the morning to synchronize your NMN consumption with your Circardian rhythms.
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Should I break down the capsule for better absorption?
Dr David Sinclair and our founder Dr Elena Seranova don't bother and just take the capsule. There are actually no studies showing that sublingual powder or powder intake results in better absorption than the capsule.
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What can amplify the effect of NMN supplementation?
Along with your NMN, take one tablespoon of extra virgin olive oil in the morning. Oleic acid, one of the ingredients in olive oil, is also shown to activate the SIRTUINS, the so-called longevity genes.
In addition, by supplementing with TMG (Trimethylglycine), you increase the methyl groups available in the cell (which NMN utilises). Adding TMG to your NMN supplementation is an excellent way to boost NMN efficiency and ensure balanced homocysteine levels.
