Promote Healthy Blood Sugar Levels & Cholesterol
After 30, our bodies don't digest carbohydrates as efficiently, and this is the reason why it's not as easy to lose excess weight after that age. Our optimised Berberine with Milk Thistle supplement helps your metabolism to overcome daily challenges, prevents the build up of insulin resistance in the blood, and promotes longevity. The optimised formula that increases the availability of Berberine from 3% to 90% with the addition of Milk Thistle, is your trusted friend when it comes to maintaining healthy blood sugar and cholesterol levels, ensuring you increase the amount of years you spend in good health.
Blood Sugar Regulation & Weight Loss
To support proper metabolism and weight loss, our blood sugar levels need to stay under control. As the years go by, the natural ability of our cells to metabolise nutrients (and especially carbohydrates) is decreasing. This often leads to insulin resistance, a process where the blood insulin spikes after a meal become higher and higher, triggering a cascade of unwanted reactions. For that reason, we might develop pre-diabetes and diabetes. This process is prevented by supplementing with Berberine.
Healthy Aging & Heart Health
To support healthy aging and robust body processes, Berberine helps you keep a healthy lipid profile, and prevents cholesterol build up. With Berberine, you're taking a proactive step toward a healthier cardiovascular system.
For individuals following the ketogenic diet, Berberine helps with entering ketosis faster after a meal, even if it was a meal containing carbohydrates like bread & pasta.
Even when someone is not obese, striving for optimal body composition and fat distribution is crucial for healthy aging. Berberine has many benefits, including the activation of AMPK, a key longevity component. AMPK activates an intracellular cleaning process called autophagy, responsible for recycling of cellular “garbage”. In a nutshell, Berberine is designed for those who seek a natural solution for metabolic and cardiovascular well-being. The science behind Berberine is compelling: it activates AMPK, which acts as a metabolic master switch, promoting energy balance and glucose regulation. This mechanism not only supports weight management but also contributes to overall vitality. Additionally, Berberine's positive influence on lipid metabolism and its anti-inflammatory properties make it an excellent choice for cardiovascular health. It's like giving your body a gentle nudge in the right direction, helping you maintain a healthy balance without any unnecessary additives or harsh chemicals.
Berberine: Recommended Daily Dosage
Take 1-2 capsules a day with or straight after your meal. If you are having a carbohydrate heavy meal such as pasta or pizza, we recommend taking 3 capsules. People with kidney or liver disease should consult with their doctor before taking any new supplements.
Berberine, a potent plant compound extracted from various herbs, has been revered for centuries for its incredible health benefits.
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Berberine Human Clinical Trials
Maintaining a healthy body and healthy weight protects us from many illnesses. Managing blood sugar and ensuring you don’t develop insulin resistance is one of the most crucial things you can do for your longevity and increasing your healthspan (the amount of time you spend in good health over the course of your life).
There are tens of human clinical studies looking into diabetic patients and prediabetics, and how they respond to Berberine supplementation. Overall, findings show that Berberine is significantly improving markers related to blood sugar control like HbA1c, fasting plasma glucose and 2-hour postprandial blood glucose amongst others. Over this meta-analysis of 46 studies, Berberine demonstrated strong evidence of improving glycemic control and overall health in thousands of participants.
In a human study of 37 men and women with metabolic syndrome took 300 milligrams of Berberine, three times a day for three months. The study concluded that they all lost an average of two inches off their waist and their BMIs went from the obese to the overweight category.
In a recent study (2020), 900 people in China between the ages of 18-75 had polyps removed during a colonoscopy. They were randomly given either 300 milligrams of Berberine twice daily or a placebo. The participants were then followed up the first year and again, the second year. The study found that none of the participants developed colorectal cancer, however, the participants taking the Berberine had fewer recurrent polyps at 36%, compared to the placebo participants with 47%.
PubMed shows the number of papers published on Berberine each year. In 2020, an astonishing 630 papers were published! As time progresses, more and more people will be aware of the outstanding benefits of supplementing with Berberine.
References
National Diabetes Statistics Report
Type 2 diabetes and quality of life
The metabolism of berberine and it’s contribution to the pharmacological effects
Extracting the benefits of berberine for colorectal cancer
Lipid-lowering effect of berberine in human subjects and rats
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FAQ
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Is your Berberine easily absorbed?
NMN Bio’s Berberine is specially formulated with the addition of Silymarin/ Milk Thistle extract to enhance bioavailability. Furthermore, by taking your Berberine with a meal or directly after a meal that includes something fatty like cheese, yoghurt or olive oil, you ensure that your supplement has enhanced absorption.
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How much Berberine should I take?
Take 1-2 capsules a day with or straight after your meal. The half life of Berberine is only a few hours, so you could either take one capsule twice a day, or if you want to push your body into autophagy in the second half of the day, you can just take 2 capsules after your last meal of the day.
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Is Berberine safe?
Berberine has been proven safe in human clinical trials with dosages up to 1.5g a day for 6 months in human subjects. In rare cases, Berberine can cause an upset stomach and digestive discomfort. But the addition of Milk Thistle in our formula lowers this risk.
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Is Berberine the same as Metformin? Should I stop my Metformin medication while taking Berberine?
Berberine is a food supplement, while Metformin is a regulated, FDA approved drug that is usually prescribed to Type II Diabetics. Both seem to be as efficient in controlling blood sugar and reducing blood glucose levels. As with any supplement, you should always consult with your doctor first before introducing any new supplements into your daily regime, and changing existing medication.