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You can always ask a question
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Does NMN have any known side effects?
The first human safety trial of NMN in humans was published in 2019 and showed that a single dose of up to 500mg was tolerable.
Three major studies of NMN are also currently underway involving human subjects. The first is being carried out by the Washington School of Medicine in St. Louis, and the second by Keio University Medical School in Tokyo, in conjunction with Washington School of Medicine. The third and perhaps most important study is being carried out by Brigham and Women's hospital in Boston, under the watchful eyes of Harvard longevity scientists. The results of these trials should be published soon.
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Why should I take NMN before breakfast?
It increases absorption.
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How much NMN should I take?
If you're younger than 35, you can start with 250mg/day and after 1-2weeks increase to 500mg to see what feels better.If you're older than 35, start with 500mg/day, then increase to 1g to see what feels better.
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Should I take one capsule in the morning and one in the afternoon?
No. Take your NMN in the morning to synchronize your NMN consumption with your Circardian rhythms.
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Should I break down the capsule for better absorption?
Dr David Sinclair and our founder Dr Elena Seranova don't bother and just take the capsule. There are actually no studies showing that sublingual powder or powder intake results in better absorption than the capsule.
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What can amplify the effect of NMN supplementation?
Along with your NMN, take one tablespoon of extra virgin olive oil in the morning. Oleic acid, one of the ingredients in olive oil, is also shown to activate the SIRTUINS, the so-called longevity genes.
In addition, by supplementing with TMG (Trimethylglycine), you increase the methyl groups available in the cell (which NMN utilises). Adding TMG to your NMN supplementation is an excellent way to boost NMN efficiency and ensure balanced homocysteine levels.