NMN Insomnia: How to Optimise Your Newfound Energy Boost
Taking NMN can make you feel so much younger that it's important to make the most of the added energy to get the best effects. If NMN's energy boost is affecting your sleep, Oh!Mg Magnesium was built to pair with it.
Sleep problems are common in older adults due to the aging process, and NMN may help address these issues by supporting the human body's natural sleep mechanisms. Oh!Mg Magnesium addresses this directly — a magnesium-based evening formula built to calm the cortisol-GABA-melatonin loop can activate when taken too late in the day.
Why NMN gives you a sudden energy surge
NMN can have such a profound impact on improving NAD+ levels, fundamental to so many vital cellular functions, that when people first start taking NMN they can be taken aback by just how much energy they suddenly have and lie awake at night.
If you are a retired pensioner and your energy has suddenly increased to what it was as a 40-year-old, then you need to start moving like you used to.
If you are 40 years old and in your younger days you used to play squash three times a week, that might be what your body is calling for again.
NMN influences the activity of sirtuins (SIRT1), which interact with core clock genes to maintain the sleep-wake cycle, especially in older adults.
NAD+ is a central mediator of cellular energy metabolism, and as we age our NAD+ levels decrease, contributing to so many aging factors we experience such as reduced energy and endurance, and just generally feeling more tired.
Which explains why when we take NMN to increase NAD+ levels, activating our ageing genes called sirtuins and suppressing the ageing process, we feel so revitalised and full of energy again.
Why you need to use that extra energy
Why is it so important to utilise this newfound energy? If you don't make the most of this energy boost, you may experience restlessness at night.
This is your body telling you it needs more activity, both physical and mental.
As your NAD+ levels improve, the boost in energy means your body will need you to increase your energy expenditure, and you should expect to feel fantastic doing it.
Risk factors for sleep issues in aging, such as physical inactivity and neurodegeneration, can contribute to insomnia, and NMN may help mitigate these risk factors.
Upping the amount of exercise you do during the day, as well as the intensity of the exercise, is the best way to spend this energy and guarantee a good night's sleep.
If you've spent years sluggish and half-asleep on the bus to work, now is a great time to get off the bus several stops earlier and enjoy a brisk walk instead.
Studies have shown significant changes in physical performance and lower limb function, such as improvements in the five-times sit-to-stand test, in older adults supplementing with NMN.
Magnesium: your secret weapon for sleep
If, while you're building up your activity to optimal levels, you're feeling wide awake and struggling to get to sleep at night, there's something else you can try.
We would advise taking magnesium one or two hours before sleep.
In fact, an estimated half of the population are believed to be magnesium deficient, so it's a fantastic mineral to take to supplement your diet anyway.
As well as helping you sleep, the benefits of taking magnesium are well-known, including reducing the risk of developing type 2 diabetes, lowering blood pressure, improved bone health, and reduced risk of cardiovascular disease and stroke.
Try taking magnesium glycinate. Glycinate is the mineral salt form of glycine, which is an amino acid essential to our central nervous system.
While we produce glycine naturally, our bodies can't keep up with their own demand. When your energy levels are increased, the body is going to struggle even more with that demand.
So, while you're at it, feel free to take both magnesium glycinate and a separate glycine supplement to maximise the beneficial effects, especially when combined with high-quality NAD+ boosting supplements.
Some foods are a great source of magnesium, including almond, cashew, and Brazil nuts, and that's right, dark chocolate too.
The reason taking magnesium glycinate works so well is because it's very readily absorbed by the body.
NMN supplementation has also been shown to improve clinical parameters and metabolite levels, which are associated with better sleep quality.
Additional benefits from taking magnesium glycinate can include improving pre-existing conditions, such as helping to manage blood sugar control in those already with diabetes and helping ease fibromyalgia symptoms.
It has also been shown to help relieve anxiety and can help alleviate PMT symptoms as well.
Exercise your mind too
Don't forget to exercise your mind as well to help you sleep.
With increased NAD+ levels, you should feel the benefits of improved mental clarity, too. Added to increased energy and endurance and put to good use, you should be completing the crossword in record time.
NMN supplementation has been shown to reduce mental fatigue and improve cognitive function in older adults, especially when combined with targeted brain health and nootropic support.
Ensuring you're intensifying both your mind and body workouts and increasing your movement in general, combined with taking magnesium at night, should see you reaping the benefits of supplementing with NMN whilst also getting a great night's sleep.
Nuclear mitochondrial communication is crucial for maintaining cellular health during the aging process, and NMN supports this communication, which may help preserve overall well-being by addressing the science behind NMN and NAD+.
What the research says about NMN and sleep
Research indicates NMN supplementation can significantly reduce sleep latency and increase the duration of deep sleep stages, leading to significant improvements in sleep quality as measured by the Pittsburgh Sleep Quality Index (PSQI), with notable reductions in daytime dysfunction and sleep disturbances.
NMN supplementation has also been linked to enhanced REM sleep latency, which is crucial for restorative sleep. A 12-week study indicated significant improvements in sleep duration and quality, with fewer awakenings during the night.
To maximise sleep benefits, NMN should generally be taken in the morning or early afternoon to avoid potential insomnia. The recommended NMN dosage by age is 250 mg daily for those under 35, increasing to 500 mg, and 500 mg for those over 35, increasing to 1,000 mg as needed.
Studies have found significant improvements in sleep quality scores, sleep duration, and reductions in daytime dysfunction among participants taking NMN.
NMN also affects neurotransmitters like GABA and serotonin, and may modulate the GABAergic system to improve insomnia symptoms.
Side effects of NMN may include temporary fatigue as the body adjusts, but it is not known to cause insomnia.
Improved sleep efficiency, meaning a higher percentage of time spent in bed is actually spent sleeping, may also be enhanced by NMN.
Preliminary studies suggest NMN could be a promising treatment for chronic insomnia, but further research is required to confirm its efficacy.
Clinical trials have shown that NMN can improve sleep issues and sleep quality changes, positively affecting sleep patterns and overall sleep health.
Nothing mentioned in this article is medical advice, and you should always consult with your doctor before taking dietary supplements.
Introduction to NMN and Sleep
NMN (Nicotinamide Mononucleotide) has emerged as a promising supplement for those seeking to improve their sleep quality and address chronic insomnia.
As research into NMN supplementation grows, studies are revealing its potential to enhance deep sleep and REM sleep, particularly in middle-aged and older adults.
One of the most widely used tools to measure sleep quality is the Pittsburgh Sleep Quality Index (PSQI), which evaluates various aspects of sleep, including sleep latency and overall restfulness.
Recent findings suggest that NMN supplementation can significantly improve PSQI scores, indicating better sleep quality and a reduction in the time it takes to fall asleep.
By understanding how NMN interacts with the body's sleep mechanisms, individuals can take proactive steps to treat chronic insomnia and enjoy more restorative, better sleep.
Whether you're struggling with poor sleep or simply looking to optimise your nightly rest, NMN may offer a pathway to a more rejuvenating sleep experience.
The Science Behind NMN
At the heart of NMN's benefits is its role as a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a vital coenzyme involved in cellular energy production and repair.
As we age, NAD+ levels naturally decline, leading to reduced energy, increased oxidative stress, and a higher risk of sleep disorders.
NMN supplementation helps replenish NAD+ stores, which can positively influence sleep quality by supporting the body's circadian rhythm and minimising sleep disturbances.
Clinical trials and in-depth NMN anti-aging reviews have demonstrated that NMN supplementation can lead to significant improvements in sleep quality, with reductions in sleep latency and increases in sleep duration, especially among older adults.
These studies highlight NMN's potential as a supportive therapy for chronic insomnia and other common sleep disorders, offering hope for those seeking to improve their sleep through science-backed interventions.
NMN and Circadian Rhythm
Our circadian rhythm, often referred to as the body's internal clock, is essential for regulating sleep-wake cycles and maintaining overall health.
As we get older, disruptions in circadian rhythm can lead to sleep disturbances, irregular sleep patterns, and deteriorating sleep quality.
NMN supplementation has been shown to help restore circadian rhythm function, resulting in better sleep quality and shorter sleep latency.
By supporting the synchronisation of the body's internal clock, NMN may help individuals experience more consistent and restful sleep patterns.
This improved regulation not only leads to better sleep but also contributes to overall well-being and a reduced risk of age-related health issues, especially when NMN is paired with complementary TMG for optimal anti-aging benefits.
Understanding the link between NMN and circadian rhythm empowers individuals to take control of their sleep quality and enjoy the benefits of a well-regulated sleep cycle.
Optimising Your Newfound Energy Boost
With NMN supplementation, many people notice a remarkable energy boost and a renewed sense of vitality.
To make the most of this newfound energy, it's important to channel it in ways that support both your daytime productivity and nighttime rest.
Personal accounts of dramatically increased productivity and energy on NMN show how powerful this shift can be when managed well.
Establishing a consistent sleep schedule helps reinforce your body's natural rhythms, while regular physical activity can further enhance sleep quality and overall health.
Incorporating stress-reducing practices such as meditation, deep breathing, or gentle stretching can also help balance increased energy levels and promote relaxation before bedtime.
Monitoring your sleep quality, perhaps by tracking changes in your sleep patterns or using tools like the PSQI, can help you fine-tune your NMN supplementation. Adjust dosage or timing as needed to achieve optimal results.
By taking a mindful approach to your energy boost, you can enjoy the full benefits of NMN supplementation and support better sleep quality every night.
Practical Strategies for Better Sleep on NMN
While NMN supplementation can significantly improve sleep quality, especially when integrated into a structured morning NAD+ support bundle, combining it with practical sleep strategies can maximise your results.
Start by setting a regular bedtime and wake-up time to help regulate your sleep-wake cycle.
Create a calming bedtime routine, such as reading, gentle stretching, or listening to soothing music, to signal to your body that it's time to wind down. Consider comprehensive longevity supplement bundles like NMN with TMG during the day to support overall recovery and sleep quality.
Limit exposure to screens and electronic devices before bed, as blue light can interfere with your ability to fall asleep.
Make your bedroom a sleep-friendly environment by keeping it cool, dark, and quiet. Pair this with thoughtfully chosen longevity and anti-aging supplements to support the restorative processes that occur during sleep.
These simple adjustments, when paired with NMN supplementation and informed by real-world NMN experiences after a month of use, can lead to better sleep and improved overall health.
Remember, it's always wise to consult with a healthcare professional before starting NMN, especially if you have underlying health conditions or are taking other medications. Discuss whether starting with NMN supplement capsules is appropriate for you.
By integrating these strategies, you can enjoy the combined benefits of NMN and good sleep hygiene for a truly restful night, especially when you tailor your regimen with 500mg NMN supplement capsules as your needs evolve.
Dr Seranova holds a master's degree in Translational Neuroscience from the University of Sheffield, UK, and a Ph.D in Stem Cell Biology and Autophagy from the University of Birmingham, UK. She is a published author in multiple peer-reviewed journals, including Cell Reports and Developmental Cell. All content on our website is put together by NMN Bio's scientific team and reviewed by Dr Elena Seranova.
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