Why do our blood sugar levels need to be regulated?
A whopping 37.3 million people across the globe have diabetes and at least 23% of adults (or more) are undiagnosed! Diabetes is the number one death caused by cardiovascular diseases and has increased by more than 25% between 1990 to 2010. Research has shown that at least 1 in every 4 adults that are diagnosed with pre-diabetes, will eventually have diabetes later on in life. The rising cases of obesity are linked to the increased number of people being diagnosed with diabetes. Diabetes leads to dysregulated levels of blood glucose which therefore transcends to an extremely increased amount of cardiovascular disease, Alzheimer disease, cancer and multiple sclerosis.
The progression of diabetes and poor glucose level control can lead to potentially life threatening complexities. Lifestyle changes including nutrition, supplementation and exercise, will need to be addressed, to improve one's quality of life.
Healthy glucose levels and increased insulin sensitivity is correlated with longevity as the dysfunction of insulin sensitivity leads to ageing.
Berberine assists with lowering blood glucose levels, and lipid metabolism, and is therefore great to have whether you would like to keep your insulin at bay or want to increase your longevity. Berberine has also been noted to have similar properties to Metformin, which is a common drug prescribed to type II diabetics in order to regulate high blood sugar and insulin resistance.
NMN Bio’s Berberine has been optimised for maximum results. Milk Thistle has been added to our formula to increase the absorption of Berberine, as taking Berberine solely, has low absorption rates, when taken orally.
Milk Thistle is a P-Glycoprotein inhibitor. P-Glycoprotein inhibits the absorption of Berberine in the gut. As a result, this mix is optimised to increase the absorption of Berberine, and provide the maximum benefit from your supplementation. Both Berberine and Milk Thistle have been shown to act together to increase insulin sensitivity and decrease the lipid levels of bad cholesterol.
Berberine as an Energy Booster and Fat Burner
Berberine has many benefits, including the activation of AMPK, a key longevity component.
Adenosine Monophosphate Kinase (AMPK) is a protein that is present in many cells. When AMPK is activated, it works to retrieve energy such as fats and carbohydrates into cells, from the bloodstream. When ATP (Adenosine Triphosphate) is depleted, and Berberine is consumed, AMPK then signals the pathways in our body to replenish ATP in the cells and increase fatty acid oxidation. Therefore, this helps to boost energy and burn fat.
A study of obese human participants taking 500 mg of Berberine 3 times per day for twelve weeks, found that there was a reduction in the participants’ body weight and blood lipid levels. In addition, their hormone levels normalised, and there was a reduction in inflammation.
AMPK is also responsible for activating autophagy, a process that helps your cells to clear out any unwanted junk, damaged organelles and toxic waste.