The Best Supplements for Menopause Brain Fog

The Best Supplements for Menopause Brain Fog

The Best Supplements for Menopause Brain Fog

Menopause, a natural phase in a woman’s life, brings about many changes, both physical and emotional, including a range of menopause symptoms. One of the most frustrating of these symptoms many women face during menopause is brain fog – a feeling of mental cloudiness, forgetfulness, and difficulty concentrating.

While this symptom can be disconcerting, there are ways to alleviate its effects and regain mental clarity. In addition to lifestyle changes and dietary adjustments, certain supplements have shown promising results in supporting cognitive function during menopause.

In this article, we’ll explore some of the best supplements for menopause brain fog and how they may help women navigate this transitional phase with greater ease.

What are Menopause Symptoms: Understanding Brain Fog

Menopause brain fog refers to a common cognitive symptom experienced by many women during perimenopause and menopause. It is characterized by a feeling of mental cloudiness, forgetfulness, difficulty concentrating, and reduced mental sharpness. Women may find it challenging to remember things, stay focused on tasks, or process information efficiently. Understanding menopause brain fog is crucial in recognizing it as a part of the menopause transition, highlighting the timing and experience of this symptom as women navigate through this phase.

Causes of Brain Fog During Menopause

The exact cause of menopause brain fog is not fully understood, but hormonal fluctuations, particularly a decline in estrogen and progesterone levels, are believed to play a significant role. Estrogen, in particular, has a profound impact on brain function, including memory, attention, and mood regulation. As estrogen levels decline during menopause, it can affect neurotransmitter activity, brain structure, and blood flow to the brain, leading to cognitive changes and symptoms like brain fog. Cognitive tests have been utilized to study the effects of these hormonal fluctuations on cognitive health during menopause, providing insights into mental alertness, reaction time, memory, and overall cognitive health in adults experiencing menopausal brain fog.

Additionally, factors such as stress, poor sleep, nutritional deficiencies, and lifestyle habits can exacerbate brain fog during menopause.

While menopause brain fog can be frustrating, it is usually temporary and can be managed with various strategies, including changes in lifestyle habits, stress management techniques, and supplementation with certain vitamins, minerals, and herbal remedies.

Top Supplements to Alleviate Brain Fog

Navigating through the fog of menopause can be challenging. However, certain supplements have shown promising results in enhancing brain health during this phase.

NAD+ Brain Blend

NMN Bio's NAD+ Brain blend is formulated with essential nutrients to help combat the cognitive symptoms commonly associated with menopause, such as brain fog and memory lapses. This specialized formula includes ingredients like phosphatidylserine (50 mg), known for its neuroprotective properties and support in maintaining neuron health and cognitive function. Additionally, the blend contains citicholine (200 mg), which enhances neurotransmitter production, empowering memory, focus, and cognitive processing.

With a strategic mix of apigenin (50 mg), this supplement helps to preserve NAD+ levels essential for cellular energy, ensuring that brain cells function efficiently during menopause. The l-tyrosine (100 mg) helps maintain dopamine levels, offering protection against cognitive decline and mood-related changes due to stress. This is particularly beneficial as stress can exacerbate brain fog during menopause.

The NAD+ Brain Blend offers a reliable solution to stay sharp and focused.

NMN (beta Nicotinamide Mononucleotide)

NMN has been hailed as the King of anti-aging supplements, and interestingly, it does have a positive impact on female hormones, pre and post menopause. Lynn Hardy, a longevity expert in her 50s, comments on the effects that NMN had on her, including better concentration and metabolism. NMN boosts a molecule called NAD+ (Nicotinamide Adenine Dinucleotide) that is the master regulator of human health. Without it, our mitochondria cannot produce ATP, or energy. And unfortunately, it declines with age, along with over 300 functions in our cells that depend on NAD+. By taking an NAD+ booster such as NMN, your NAD+ levels are replenished within 2 weeks, and brain fog is reduced. It has multiple other beneficial effects, such as helping with arthritis pain and symptoms that menopausal women may struggle.

Ginkgo Biloba

Ginkgo biloba is a popular herbal supplement known for its cognitive-enhancing properties. It works by improving blood flow to the brain, increasing oxygen delivery, and protecting against oxidative stress.

Research shows that ginkgo biloba may help alleviate memory problems and cognitive decline, a symptom of menopausal brain fog. Research has also found that ginkgo biloba has beneficial effects on cognitive performance and activities of daily living in individuals with dementia.

These studies highlight ginkgo biloba's potential to improve cognitive performance, which may be beneficial for those experiencing memory loss and other cognitive issues associated with menopausal brain fog.

Omega-3 Essential Fatty Acids

Omega-3 fatty acids, found in fish oil supplements, have been studied extensively for their brain-boosting benefits. These essential fats support brain health by reducing inflammation, improving communication between brain cells, and enhancing mood.

Research suggests that omega-3 supplementation may help alleviate cognitive decline and memory problems associated with menopause. Deficiencies in these fatty acids have also been linked to mood disorders, which can exacerbate menopause brain fog symptoms.

Vitamin B Complex

The B vitamins, including B6, B12, and folate, play crucial roles in brain function and mental clarity. During menopause, hormonal changes can impact the body’s ability to absorb and utilize these vitamins effectively.

Supplementing with a B-complex can help support cognitive function, energy production, and mood regulation, thus combating menopause-related brain fog. For example, research suggests that Vitamin B supplements might delay or maintain the cognitive decline of elderly adults.

Similarly, vitamin C plays a pivotal role in brain health, particularly in preventing cognitive decline and enhancing cognitive function. Adequate levels of vitamin C are linked with improved memory, attention, mood, and overall brain health. Vitamin C deficiency, on the other hand, is associated with cognitive impairment, depression, and confusion. Maintaining sufficient vitamin C levels may thus be crucial for improving brain function and reducing symptoms of brain fog, especially during menopause when nutritional needs and the body's ability to process nutrients may change. The best, natural, multivitamin to take would be desiccated beef liver in capsules, as it contains most Vitamins B, C, Iron and is a natural source for multiple other nutrients. 

Rhodiola Rosea

Rhodiola rosea is an adaptogenic herb that helps the body adapt to stress and improve resilience. It's packed with neuroprotective and cardioprotective properties, making it a powerful ally for brain health.

During menopause, stress levels can soar, exacerbating symptoms like brain fog and mental fatigue. Rhodiola rosea supplementation may help reduce stress-related cognitive impairments, enhance mental clarity, and promote overall well-being.

Studies have shown that Rhodiola rosea can significantly improve neuropsychological symptoms. These include fatigue, anxiety, depression, and stress intolerance, all of which can contribute to brain fog.


Resveratrol is a noteworthy supplement for combating menopausal brain fog. This compound, though relatively new to the health scene, has shown promising results in enhancing cerebrovascular function.

Studies indicate that it can improve regional blood flow, particularly when the brain is under cognitive stress. This leads to enhancements in mood, perception of well-being, and short-term memory.

Moreover, resveratrol has been linked to improved mental performance and reasoning. It also aids in maintaining attention and concentration, which are often compromised during menopause.

Vitamin E and Antioxidants

Vitamin E and antioxidants play crucial roles in combating brain fog by neutralizing harmful free radicals and supporting overall brain health. Free radicals, which are byproducts of normal metabolism and environmental toxins, can cause oxidative stress in the brain, leading to cognitive decline and memory problems associated with brain fog.

Vitamin E, a powerful antioxidant, helps protect brain cells from oxidative damage by scavenging free radicals and reducing inflammation. Additionally, antioxidants found in fruits, vegetables, and other sources can also contribute to brain health by enhancing blood flow, promoting nerve cell growth, and improving communication between brain cells.

By counteracting oxidative stress and supporting various brain functions, Vitamin E supplements offer potential benefits in reducing the severity of brain fog and improving cognitive clarity. This is evident as studies show that high plasma Vitamin E levels have been associated with better cognitive performance in the aging population and dementia and Alzheimer’s disease patients.

Equally important for brain health and cognitive function is vitamin D. Low levels of vitamin D can negatively impact cognitive health, contributing to symptoms like brain fog. Vitamin D deficiency may worsen cognitive decline, increase the risk of depressive symptoms, and impair memory, concentration, and overall mental well-being. Supplementing with vitamin D, especially in individuals with low or deficient levels, may help improve these cognitive functions and mood, offering a complementary approach to antioxidants in mitigating menopause brain fog.

Additional Natural Ways to Combat Menopausal Brain Fog

  • Regular Exercise. Physical exercise is more than just a way to keep your body in shape; it's a natural method to combat menopause brain fog. When you engage in regular physical activity, it increases blood flow to your brain, enhancing cognitive function and memory.

    Not to mention, exercise releases endorphins, the body's natural mood lifters. This can help alleviate some of the emotional symptoms associated with menopause, such as mood swings and depression.

    It's not about the intensity of the workout, but consistency. Find an activity you enjoy and stick with it. Your brain will thank you.

  • Mindfulness and Meditation. From being present in the moment with your loved ones, to guided meditation, putting in place "anchors" that reset your nervous system during the day may be helpful. This also includes open communication and self-expression, with the important people in your life, and this strategy can be part of your stress management. Stress management is a crucial part of tackling menopause brain fog. It's no secret that menopause can be a stressful period, with hormonal changes and symptoms like hot flashes adding to the anxiety. One natural way to manage this stress is through open communication. Talk about your concerns with a trusted friend, family member, or healthcare professional. It's okay to seek help and express your feelings. Another great stress buster is laughter. It's not just a saying, laughter truly can be the best medicine. Find things that make you smile and keep your spirits high.

  • Healthy Diet. A balanced diet is a secret weapon against menopause brain fog. It's not just about eating less junk food, but also about incorporating brain-boosting nutrients. Omega-3 fatty acids, antioxidants, and B vitamins are your brain's best friends. They're found in foods like fish, nuts, seeds, and colorful fruits and veggies.

    The MIND diet, a combo of the Mediterranean and DASH diets, is a great guide. It's packed with whole grains, leafy greens, and berries, and it's been linked to lower rates of cognitive decline.

    Don't forget about foods rich in Vitamin D and those that restore gut health. Mushrooms, eggs, and fermented items like kombucha and sauerkraut can do wonders.

    And here's a fun fact: eating soy has been shown to improve memory in menopausal women. So, tofu stir-fry, anyone?

  • Quality Sleep. Sleep, often overlooked, plays a pivotal role in battling menopause brain fog. It's during those hours of shut-eye that your brain gets a chance to rest and rejuvenate.

    A lack of quality sleep can leave you feeling groggy and foggy-headed. It's like trying to navigate through a maze with a blindfold on.

    A well-rested brain is a fog-free brain. So, make sleep a priority in your fight against menopause brain fog.

  • Brain-Training Activities. Mental exercise is a crucial weapon in your arsenal against menopause brain fog. It's not just about Sudoku or crosswords, it's about keeping your brain active and engaged in various ways.

    You could try learning a new language or picking up a musical instrument. These activities not only stimulate your brain but also bring a sense of accomplishment and joy.

    Remember, the goal isn't to become a master but to challenge your brain and keep it sharp. So, don't shy away from trying something new and exciting.

    In the fight against menopause brain fog, mental exercise is a natural way to keep your mind clear and focused. So, flex those brain muscles and keep the fog at bay!

  • Looking for more ways to optimize cognitive function? Herbal Teas can be one way, along with proper daily hydration, limiting alcohol and caffeine (as both of these actually dehydrate you!) and staying social on a regular basis.


Final Thoughts on Managing Menopausal Brain Fog

Menopausal women experiencing brain fog have several options to support their cognitive health and improve memory amidst this transitional phase of life. While consulting with a healthcare professional is recommended, incorporating supplements such as NMN Bio's NAD+ Brain Blend into one's daily regimen can provide valuable support.

Alongside supplementation, adopting a holistic approach that includes lifestyle modifications like regular exercise, mindfulness practices, a healthy diet, quality sleep, brain-training activities, and social connection can further bolster cognitive resilience and combat poor concentration associated with menopausal brain fog.

By taking proactive steps and leveraging the power of natural remedies, women can navigate through menopause with greater mental clarity and well-being.

Researched and reviewed by Dr Elena Seranova, Ph.D.

Dr Seranova holds a master's degree in Translational Neuroscience from the University of Sheffield, UK, and a Ph.D in Stem Cell Biology and Autophagy from the University of Birmingham, UK. She is a published author in multiple peer-reviewed journals, including Cell Reports and Developmental Cell.


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